In case you missed some earlier information, Mass Effect: Andromeda story starts before the Reaper invasion but after the story of Mass Effect 1 and is focused on the Andromeda Initiative, a civilian, multi-species project created to send scientists, explorers and colonists on a one-way trip to settle in the Andromeda Galaxy.
The new 4-minute long trailer, which you can check out below, provides a glimpse into some of the new worlds, but also shows characters like Krogan and Turian that can be added to the squad. The trailer also shows a bit more details about the Nomad, a vehicle that is similar to the Mako and allows you to move around each planet
Mass Effect: Andromeda is scheduled to be released in Spring 2017 on PC, PlayStation 4, PlayStation 4 Pro, and Xbox One.