Probably a sequel rather than a spin-off

Firaxis and 2K Games have confirmed that a new Civilization game is now under development.

Optimizations for Civilization VI, some fixes

AMD has released its newest Radeon Software Crimson Edition 16.11.4 drivers which are supposed to bring optimizations for Sid Meier's Civilization VI game as well as a couple of fixes.

And systems with RX 480

AMD has added yet another game to its promotion page,  Sid Meier's Civilization VI, which will be available with the Radeon RX 480.